No. At Renova, PDGF is applied topically as a concentrate after microneedling or ProFractional treatment, allowing it to penetrate deeper into the skin through the micro-channels created by those procedures.
What PDGF Therapy Is
Looking for a PDGF under-eye treatment in Carmel, Indiana? Renova Aesthetics offers PDGF (Platelet-Derived Growth Factor) therapy, a topical regenerative treatment applied after microneedling or ProFractional to accelerate collagen remodeling and restore youthful, brighter under-eyes — without injections or fillers.
PDGF is a naturally occurring protein in your blood responsible for healing and tissue regeneration. In aesthetic medicine, it’s extracted and concentrated into a topical concentrate that’s applied to the skin immediately after microneedling or ProFractional treatment. The micro-channels created during those procedures allow the PDGF concentrate to penetrate deeper into the dermis, where it can activate cellular repair, boost collagen and elastin production, and support healthier skin from within.
About PDGF Therapy
Treatment Type
Regenerative Skin Treatment
Recovery Time
Minimal to none (especially when used topically or post-procedure)
Treatment Length
30–60 minutes depending on area
What it Treats
PDGF can be applied to both skin and scalp. Common treatment areas include:
- Under-eye hollowness and dark circles
- Fine lines and skin laxity
- Dull or uneven skin tone
- Acne scars and texture concerns
- Thinning hair or early-stage hair loss
- Post-laser healing and skin recovery support


How PDGF Works
PDGF initiates a cascade of cellular repair by stimulating fibroblast activity (the cells that produce collagen and elastin), enhancing angiogenesis (new blood vessel formation), supporting wound healing and skin barrier restoration, and promoting hair follicle regeneration. This targeted biologic therapy creates a healthier skin matrix and scalp environment, improving tone, texture, and firmness over time.


PDGF + Microneedling: A Powerful Pairing
Combining PDGF with RF microneedling or traditional microneedling amplifies its effects. The micro-channels created during treatment allow the PDGF concentrate to penetrate deeper, where it can activate regeneration at the cellular level — accelerating healing, enhancing collagen synthesis, and delivering more visible, longer-lasting results than either treatment alone.
Why We Offer PDGF at Renova
Renova Aesthetics is a leader in regenerative aesthetics and combination therapies. As part of our STAX™ approach, we integrate medical-grade biologics like PDGF into personalized treatment plans to accelerate recovery after laser or microneedling, improve treatment outcomes, minimize downtime, and support long-term skin health. Our providers receive advanced training annually and use VISIA® skin analysis to track improvements in real time.


Who This Is For
PDGF is safe for all skin types and ideal for anyone looking to restore vibrancy to aging or dull skin, boost results from microneedling, laser, or RF treatments, naturally stimulate hair growth without medication, or heal faster post-procedure with less inflammation — especially clients seeking under-eye rejuvenation without fillers.


Finding a PDGF Under-Eye Treatment Near Me in Carmel, Indiana
If you’ve been searching for a PDGF under-eye treatment, Renova Aesthetics delivers it as a topical concentrate paired with microneedling or ProFractional — not an injection — for a regenerative approach to hollow, tired-looking under-eyes.


Want to find out if PDGF is right for your skin or scalp concerns? Request a consultation or VISIA® skin analysis with our expert team in Carmel, IN. Skin & laser consultations require a $75 nonrefundable consultation fee, which will be applied toward an eligible treatment.
The Renova Way
Knowledge & Expertise
You can trust our highly skilled team to reveal the most beautiful you. Our team members are experienced professionals who are enthusiastic about skin care and providing you with the best experience possible—the Renova experience.
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The Renova Way
Comfortable Atmosphere
Behind your exceptional results, your comfort is our top priority before, during, and after treatment. We will always ensure any questions you may have are answered and that you are confident in your treatment.
02
The Renova Way
Luxury Experience
Our state-of-the-art facility and advanced treatment modalities make for a luxury medical spa experience in Carmel. You can trust that Renova is providing nothing but the best when it comes to your care.
03
Physician-Led Aesthetic Care
At Renova Aesthetics, exceptional results begin with exceptional medical care. We combine the art of aesthetics with a physician-led approach that prioritizes patient safety, clinical excellence, and natural-looking outcomes.
A Higher Standard of Clinical Oversight
Medical aesthetic treatments are delivered within a physician-directed model of care, supported by established clinical protocols, ongoing physician oversight, and regular quality assurance through clinical chart reviews.
Expertise That Never Stops Evolving
Our team participates in advanced continuing education and hands-on training to remain at the forefront of aesthetic medicine, ensuring every treatment reflects the latest techniques and best practices.
Personalized Planning, Backed by Technology
Before receiving medical treatments, each patient completes a Good Faith Examination (GFE) with a qualified medical provider to confirm candidacy, discuss goals, review medical history, and develop a personalized treatment plan. When appropriate, advanced technology such as VISIA® Skin Analysis helps us objectively evaluate your skin and create customized recommendations based on your unique anatomy and aesthetic goals.
The Renova Standard
Whether you’re considering injectables, laser treatments, or skin rejuvenation therapies, you can feel confident knowing your care is being guided by experienced medical leadership and delivered by highly trained providers committed to consistency, precision, and exceptional patient experiences.
Because when medicine, science, and artistry come together, beautiful results follow. That’s the Renova standard.
Stimulate your body’s natural healing abilities
Request a consultation with one of our specialized aesthetics providers to see what PDGF Therapy can do for you.
Skin & laser consultations require a $75 nonrefundable consultation fee, which will be applied toward an eligible treatment.
FAQ
Most clients begin to see improvement in brightness and texture within a few weeks, with continued collagen-building benefits over the following months.
Yes. PDGF is a popular filler-free option for under-eye rejuvenation, working by stimulating your body’s own collagen production rather than adding volume.
PDGF is most commonly paired with RF microneedling or traditional microneedling, and can also complement ProFractional, BBL, Halo, HydraFacial, or hair restoration treatments.
Downtime is minimal to none, especially since PDGF is applied topically after your microneedling or ProFractional session.






